3-Aminomethyl-1-N-Fmoc-piperidine hydrochloride

3-Aminomethyl-1-N-Fmoc-piperidine hydrochloride - Names and Identifiers

Name	9H-fluoren-9-ylmethyl 3-(aminomethyl)piperidine-1-carboxylate hydrochloride
Synonyms	3-AMinoMethyl-1-N-FMoc-piperidine HCl 1-FMoc-3-AMinoMethylpiperidine hydrochloride 3-Aminomethyl-1-N-Fmoc-piperidine hydrochloride 9H-Fluoren-9-ylmethyl 3-(aminomethyl)piperidine-1-carboxylate hydrochloride 9H-fluoren-9-ylmethyl 3-(aminomethyl)piperidine-1-carboxylate hydrochloride 3-(Aminomethyl)-1-piperidinecarboxylic acid 9H-fluoren-9-ylmethyl ester hydrochloride 3-(Aminomethyl)-1-piperidinecarboxylic acid 9H-fluoren-9-ylmethyl ester monohydrochloride
CAS	669713-56-8
InChI	InChI=1/C21H24N2O2.ClH/c22-12-15-6-5-11-23(13-15)21(24)25-14-20-18-9-3-1-7-16(18)17-8-2-4-10-19(17)20;/h1-4,7-10,15,20H,5-6,11-14,22H2;1H

3-Aminomethyl-1-N-Fmoc-piperidine hydrochloride - Physico-chemical Properties

Molecular Formula	C21H25ClN2O2
Molar Mass	372.89
Boling Point	509.2°C at 760 mmHg
Flash Point	261.7°C
Vapor Presure	1.74E-10mmHg at 25°C
Storage Condition	Inert atmosphere,Room Temperature

3-Aminomethyl-1-N-Fmoc-piperidine hydrochloride - Risk and Safety

Hazard Class

IRRITANT

3-Aminomethyl-1-N-Fmoc-piperidine hydrochloride - Introduction

9H-fluoren-9-ylmethyl 3-(aminomethyl)piperidine-1-carboxylate hydrochloride is an organic compound with the chemical formula C27H27N2O2 · HCl. The following is a description of the nature, use, preparation and safety information:

Nature:
-Appearance: White or off-white solid
-Melting point: about 150-155°C
-Molecular weight: 446.98g/mol
-Solubility: Soluble in chloroform, dichloromethane and ethanol

Use:
- 9H-fluoren-9-ylmethyl 3-(aminomethyl)piperidine-1-carboxylate hydrochloride is a commonly used organic synthesis reagent, which is commonly used in protecting group reactions in peptide and protein synthesis.
-It can remove the Fmoc protecting group through a deprotection reaction, thereby exposing the amino functional group for further functional modification.

Preparation Method:
-9H-fluoren-9-ylmethyl 3-(aminomethyl)piperidine-1-carboxylate hydrochloride can be synthesized through a series of chemical reactions. The specific synthesis route may vary according to actual conditions. A common synthetic method is the reaction of 3-aminomethyl-1-piperidinemethanol with 9-fluorenecarbonyl chloride, followed by reaction with hydrochloric acid to produce the hydrochloride salt form.

Safety Information:
- 9H-fluoren-9-ylmethyl 3-(aminomethyl)piperidine-1-carboxylate hydrochloride may be harmful to health, so appropriate safety measures need to be taken during use.
-Avoid contact with skin and eyes during operation. In case of contact, rinse immediately with plenty of water and seek medical help.
-When storing and handling, keep away from ignition and oxidizing agents to avoid fire or explosion.
-Follow proper laboratory practices when using, and pay attention to personal protective measures, such as wearing protective glasses and gloves.
-When it comes to waste disposal, local regulations must be observed.

Last Update：2024-04-10 22:29:15